cees dekker Things To Know Before You Buy
Utilizing one-molecule optical and AFM imaging and pressure-spectroscopy tactics, we seek out to unravel the mechanistic elements of the structure and dynamics of chromosomes. Our research pursuits include things like:But how do morality, the dignity from the individual, my knowledge in the meaning of everyday living, observe through the movement of atoms? A purely naturalistic perspective fails in this article; a Christian point of view, I think, is a way more sensible way to interpret these areas of actuality.’
Dynamics of initiation, termination and reinitiation of DNA translocation through the motor protein EcoR124I
Deposition and atomic drive microscopy of unique phthalocyanine polymers concerning nanofabricated electrodes
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Our analysis ranges in the biophysics of DNA to artificial cells and over and above. Please take a look beneath at the spectrum of our latest tasks.
‘At the beginning we checked out Organic units which has a Actual physical perspective and acted on The premise with the applications we realized. It took a several years in advance of we started off Performing additional on the massive biological concerns. I then began to phone it nanobiology, a phrase that did not exist at the time.
Movement-driven rotary motors such as windmills and h2o wheels travel functional procedures in human Modern society. Despite the fact that examples of this sort of rotary motors also function prominently in cell biology, their artificial development on the nanoscale has remained tough. Right here we demonstrate move-pushed rotary motion of a self-structured DNA nanostructure that is certainly docked onto a nanopore in a thin good-condition membrane. An elastic DNA bundle self-assembles into a chiral conformation on phoretic docking on to the sound-state nanopore, and subsequently displays a sustained unidirectional rotary movement of up to 20 rev s−one.
Knowing fundamental procedures regulating the spatial and dynamic organisation with the DNA in Dwell cells.
But carbon nanotubes have remained a analysis topic of sizeable curiosity to numerous. In truth, the outlook on working with carbon nanotubes to construct practical equipment, in regions like radio-frequency electronics, electronic electronics and flexible electronics, continues to be vivid.
An integrated microfluidic System for quantifying drug permeation throughout biomimetic vesicle membranes
Many ceesdekker.net new phenomena ended up found, and he and his research group established a number one position With this area of investigate. Dekker and his investigation group uncovered new physics of nanotubes in addition to explored the feasibility of molecular electronics. In 1998, they ended up the very first to make a transistor depending on only one nanotube molecule.
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Case in point (2) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is shown in grey, the rim with the pore is highlighted in red, plus a 3D rendering of the motion with the DNA rod is displayed.